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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
PCBP1_HUMAN
USC-OGP 2-DE database
:
PCBP1_HUMAN
PCBP1_HUMAN
General information about the entry
View entry in simple text format
Entry name
PCBP1_HUMAN
Primary accession number
Q15365
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Poly(rC)-binding protein 1; AltName: Full=Alpha-CP1; AltName: Full=Heterogeneous nuclear ribonucleoprotein E1; Short=hnRNP E1; AltName: Full=Nucleic acid-binding protein SUB2.3;.
Gene name
Name=PCBP1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0431
:
pI=6.35; Mw=40313
PLATELET_6-11
{PLATELET 6-11}
Homo sapiens (Human)
map experimental info
PLATELET_6-11
MAP LOCATIONS:
SPOT OGP-0957
:
pI=6.71; Mw=39701
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1195
:
pI=6.77; Mw=40578
SPOT OGP-1196
:
pI=6.47; Mw=40351
SPOT OGP-1198
:
pI=6.93; Mw=39899
SPOT OGP-1200
:
pI=7.15; Mw=39675
Cross-references
UniProtKB/Swiss-Prot
Q15365; PCBP1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
PCBP1_HUMAN
Primary accession number
Q15365
Secondary accession number(s)
Q13157 Q14975
Sequence was last modified on
February 16, 2004 (version 2)
Annotations were last modified on
March 15, 2017 (version 174)
Name and origin of the protein
Description
RecName: Full=Poly(rC)-binding protein 1; AltName: Full=Alpha-CP1; AltName: Full=Heterogeneous nuclear ribonucleoprotein E1; Short=hnRNP E1; AltName: Full=Nucleic acid-binding protein SUB2.3;
Gene name
Name=PCBP1
Encoded on
Name=PCBP1
Keywords
3D-structure
;
Acetylation
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
DNA-binding
;
Nucleus
;
Phosphoprotein
;
Reference proteome
;
Repeat
;
Ribonucleoprotein
;
RNA-binding
;
Viral RNA replication
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X78137; CAA55016.1
; -; mRNA
EMBL
U24223; AAA91317.1
; -; mRNA
EMBL
Z29505; CAA82631.1
; ALT_FRAME; mRNA
EMBL
BC039742; AAH39742.1
; -; mRNA
CCDS
CCDS1898.1; -
; .
RefSeq
NP_006187.2; NM_006196.3
; .
UniGene
Hs.2853; -
; .
PDB
1WVN; X-ray
; 2.10 A; A=279-356
PDB
1ZTG; X-ray
; 3.00 A; A/B/C/D=14-85
PDB
3VKE; X-ray
; 1.77 A; A/B/C/D=14-86
PDBsum
1WVN; -
; .
PDBsum
1ZTG; -
; .
PDBsum
3VKE; -
; .
ProteinModelPortal
Q15365; -
; .
SMR
Q15365; -
; .
BioGrid
111126; 169
; .
DIP
DIP-38136N; -
; .
IntAct
Q15365; 88
; .
MINT
MINT-96267; -
; .
STRING
9606.ENSP00000305556; -
; .
iPTMnet
Q15365; -
; .
PhosphoSitePlus
Q15365; -
; .
SwissPalm
Q15365; -
; .
BioMuta
PCBP1; -
; .
DMDM
42560548; -
; .
OGP
Q15365; -
; .
REPRODUCTION-2DPAGE
IPI00016610; -
; .
UCD-2DPAGE
Q15365; -
; .
EPD
Q15365; -
; .
PaxDb
Q15365; -
; .
PeptideAtlas
Q15365; -
; .
PRIDE
Q15365; -
; .
DNASU
5093; -
; .
Ensembl
ENST00000303577; ENSP00000305556
; ENSG00000169564; .
GeneID
5093; -
; .
KEGG
hsa:5093; -
; .
CTD
5093; -
; .
DisGeNET
5093; -
; .
GeneCards
PCBP1; -
; .
HGNC
HGNC:8647; PCBP1
; .
HPA
CAB037113; -
; .
HPA
HPA043803; -
; .
HPA
HPA068497; -
; .
MIM
601209; gene
; .
neXtProt
NX_Q15365; -
; .
OpenTargets
ENSG00000169564; -
; .
PharmGKB
PA32986; -
; .
eggNOG
KOG2190; Eukaryota
; .
eggNOG
ENOG410XNN8; LUCA
; .
GeneTree
ENSGT00760000119144; -
; .
HOGENOM
HOG000182823; -
; .
HOVERGEN
HBG053520; -
; .
InParanoid
Q15365; -
; .
KO
K12889; -
; .
OMA
TIAGMPQ; -
; .
OrthoDB
EOG091G0DHI; -
; .
PhylomeDB
Q15365; -
; .
TreeFam
TF318292; -
; .
Reactome
R-HSA-72163; mRNA Splicing - Major Pathway
; .
Reactome
R-HSA-72203; Processing of Capped Intron-Containing Pre-mRNA
; .
ChiTaRS
PCBP1; human
; .
EvolutionaryTrace
Q15365; -
; .
GeneWiki
PCBP1; -
; .
GenomeRNAi
5093; -
; .
PRO
PR:Q15365; -
; .
Proteomes
UP000005640; Chromosome 2
; .
Bgee
ENSG00000169564; -
; .
CleanEx
HS_PCBP1; -
; .
ExpressionAtlas
Q15365; baseline and differential
; .
Genevisible
Q15365; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:BHF-UCL; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0016607; C:nuclear speck
; IDA:HPA; .
GO
GO:0005654; C:nucleoplasm
; IDA:HPA; .
GO
GO:0000932; C:P-body
; IDA:HPA; .
GO
GO:0045296; F:cadherin binding
; IDA:BHF-UCL; .
GO
GO:0003729; F:mRNA binding
; IDA:BHF-UCL; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0000981; F:RNA polymerase II transcription factor activity
; sequence-specific DNA binding; IEA:Ensembl
GO
GO:0098847; F:sequence-specific single stranded DNA binding
; IEA:Ensembl; .
GO
GO:0003697; F:single-stranded DNA binding
; IDA:UniProtKB; .
GO
GO:0010467; P:gene expression
; TAS:Reactome; .
GO
GO:0000398; P:mRNA splicing
; via spliceosome; TAS:Reactome
GO
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter
; IEA:Ensembl; .
GO
GO:0039694; P:viral RNA genome replication
; IDA:UniProtKB; .
Gene3D
3.30.1370.10; -
; 3; .
InterPro
IPR004087; KH_dom
; .
InterPro
IPR004088; KH_dom_type_1
; .
Pfam
PF00013; KH_1
; 3; .
SMART
SM00322; KH
; 3; .
SUPFAM
SSF54791; SSF54791
; 3; .
PROSITE
PS50084; KH_TYPE_1
; 3; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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